YtdI

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  • Description: inorganic polyphosphate/ATP-NAD kinase

Gene name ytdI
Synonyms ppnKB
Essential no
Product inorganic polyphosphate/ATP-NAD kinase
Function generation of NADP from NAD
Gene expression levels in SubtiExpress: ytdI
MW, pI 30 kDa, 6.49
Gene length, protein length 801 bp, 267 aa
Immediate neighbours sppA, ytcJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YtdI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtdI expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29540

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + NAD+ = ADP + NADP+ (according to Swiss-Prot)
  • Protein family: NAD kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1YT5 (from Thermotoga maritima) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

Vaheh Oganesyan, Candice Huang, Paul D Adams, Jaru Jancarik, Hisao A Yokota, Rosalind Kim, Sung-Hou Kim
Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2005, 61(Pt 7);640-6
[PubMed:16511117] [WorldCat.org] [DOI] (I p)