Difference between revisions of "YtdI"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29540 ytdI]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29540 ytdI]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YtdI YtdI]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 6.49   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30 kDa, 6.49   

Revision as of 11:48, 8 April 2014

  • Description: inorganic polyphosphate/ATP-NAD kinase

Gene name ytdI
Synonyms ppnKB
Essential no
Product inorganic polyphosphate/ATP-NAD kinase
Function generation of NADP from NAD
Gene expression levels in SubtiExpress: ytdI
Metabolic function and regulation of this protein in SubtiPathways:
YtdI
MW, pI 30 kDa, 6.49
Gene length, protein length 801 bp, 267 aa
Immediate neighbours sppA, ytcJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YtdI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtdI expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29540

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + NAD+ = ADP + NADP+ (according to Swiss-Prot)
  • Protein family: NAD kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1YT5 (from Thermotoga maritima) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Martin Lehnik-Habrink, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, Christina Herzberg, Jörg Stülke
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Mol Microbiol: 2011, 81(6);1459-73
[PubMed:21815947] [WorldCat.org] [DOI] (I p)

Vaheh Oganesyan, Candice Huang, Paul D Adams, Jaru Jancarik, Hisao A Yokota, Rosalind Kim, Sung-Hou Kim
Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2005, 61(Pt 7);640-6
[PubMed:16511117] [WorldCat.org] [DOI] (I p)