YtcG

• Description: putative negative regulator of transcription of ribonucleotide reductase nrd genes and operons
  
  

Gene name	ytcG
Synonyms	nrdR
Essential	no
Product	putative regulator protein
Function	unknown
Gene expression levels in SubtiExpress: ytcG
MW, pI	17 kDa, 8.05
Gene length, protein length	456 bp, 152 aa
Immediate neighbours	dnaB, speD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

The gene

Basic information

• Locus tag: BSU29000

Database entries

• BsubCyc: BSU29000

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: nrdR family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU29000

• Structure:

• UniProt: Q45549

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ytcG PubMed

• Expression browser: ytcG PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Inna Grinberg, Tanya Shteinberg, Batia Gorovitz, Yair Aharonowitz, Gerald Cohen, Ilya Borovok
The Streptomyces NrdR transcriptional regulator is a Zn ribbon/ATP cone protein that binds to the promoter regions of class Ia and class II ribonucleotide reductase operons.
J Bacteriol: 2006, 188(21);7635-44
[PubMed:16950922] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)