ytcB

168

putative UDP-glucose epimerase

locus: BSU_30870

Molecular weight: 34.76 kDa

pI: 8.87

Protein length: 316 aa

Gene length: 951 bp

function: unknown

product: putative UDP-glucose epimerase

essential: no

synonyms: ytcB

List of homologs in different organisms, belongs to COG0451 (Galperin et al., 2021)

Gene

Coordinates: 3,157,008  3,157,958

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The protein

Protein family

• [wiki|NAD(P)-dependent epimerase/dehydratase family] (according to UniProt)

Structure

• [PDB|1SB8] (Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase, 34% identity) [Pubmed|15016816], [PDB|5U4Q] (from Klebsiella pneumoniae 35% identity)
• [AF|O34886]

Paralogous protein(s)

• [protein|9836E90BD443F5269A43E5C69FCF2CCB22EDF65B|yfnG], (29,5%)

Biological materials

Mutant

• MGNA-A279 (ytcB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/279 NBRP B. subtilis, Japan]
• BKE30870 ([gene|A51B5F9F86D2F7B690712B9EC181B1C07B312E02|ytcB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30870 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGCTGCTCCTGTGACGAGTA,  downstream forward: _UP4_TCGCTGTATCAGGGGGAATA
• BKK30870 ([gene|A51B5F9F86D2F7B690712B9EC181B1C07B312E02|ytcB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30870 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CGCTGCTCCTGTGACGAGTA,  downstream forward: _UP4_TCGCTGTATCAGGGGGAATA

References

• 22383849,26577401,15016816