YtbE

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  • Description: putative aldo/keto reductase, may be involved in detoxification

Gene name ytbE
Synonyms
Essential yes PubMed
Product putative aldo/keto reductase
Function unknown
Gene expression levels in SubtiExpress: ytbE
MW, pI 31 kDa, 4.786
Gene length, protein length 840 bp, 280 aa
Immediate neighbours ytbD, ytaG
Sequences Protein DNA DNA_with_flanks
Genetic context
YtbE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtbE expression.png















Categories containing this gene/protein

poorly characterized/ putative enzymes, membrane proteins, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29050

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: Nudix hydrolase, aldo/keto reductase family (according to Swiss-Prot)
  • Paralogous protein(s): YvgN

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jian Lei, Yan-Feng Zhou, Lan-Fen Li, Xiao-Dong Su
Structural and biochemical analyses of YvgN and YtbE from Bacillus subtilis.
Protein Sci: 2009, 18(8);1792-800
[PubMed:19585557] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)