YszB

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  • Description: chorismate mutase

Gene name pheB
Synonyms
Essential no
Product chorismate mutase
Function biosynthesis of phenylalanine
Gene expression levels in SubtiExpress: pheB
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 16 kDa, 6.36
Gene length, protein length 441 bp, 147 aa
Immediate neighbours pheA, obg
Sequences Protein DNA DNA_with_flanks
Genetic context
PheB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PheB expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU27910

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0735 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Frederik Claeyssens, Kara E Ranaghan, Narin Lawan, Stephen J Macrae, Frederick R Manby, Jeremy N Harvey, Adrian J Mulholland
Analysis of chorismate mutase catalysis by QM/MM modelling of enzyme-catalysed and uncatalysed reactions.
Org Biomol Chem: 2011, 9(5);1578-90
[PubMed:21243152] [WorldCat.org] [DOI] (I p)

K Trach, J A Hoch
The Bacillus subtilis spo0B stage 0 sporulation operon encodes an essential GTP-binding protein.
J Bacteriol: 1989, 171(3);1362-71
[PubMed:2537815] [WorldCat.org] [DOI] (P p)