YsnA

• Description: ITPase
  
  

Gene name	ysnA
Synonyms
Essential	no
Product	ITPase
Function	purine metabolism
Gene expression levels in SubtiExpress: ysnA
Metabolic function and regulation of this protein in SubtiPathways: Thiamin
MW, pI	21 kDa, 4.95
Gene length, protein length	594 bp, 198 aa
Immediate neighbours	ysnB, rph
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

nucleotide metabolism/ other

The gene

Basic information

• Locus tag: BSU28360

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: NTP + H₂O = NDP + phosphate (according to Swiss-Prot)

• Protein family: HAM1 NTPase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2MJP (from Methanococcus jannaschii) PubMed

• UniProt: P94558

• KEGG entry: [2]

• E.C. number: 3.6.1.15

Expression and regulation

• Operon:

• Expression browser: ysnA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

S Lin, A G McLennan, K Ying, Z Wang, S Gu, H Jin, C Wu, W Liu, Y Yuan, R Tang, Y Xie, Y Mao
Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene.
J Biol Chem: 2001, 276(22);18695-701
[PubMed:11278832] [WorldCat.org] [DOI] (P p)

K Y Hwang, J H Chung, S H Kim, Y S Han, Y Cho
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Nat Struct Biol: 1999, 6(7);691-6
[PubMed:10404228] [WorldCat.org] [DOI] (P p)