Difference between revisions of "YsnA"

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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ysnA_2900545_2901141_-1 ysnA] {{PubMed|22383849}}
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=Biological materials =
 
=Biological materials =

Revision as of 14:38, 16 April 2012

  • Description: ITPase

Gene name ysnA
Synonyms
Essential no
Product ITPase
Function purine metabolism
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 21 kDa, 4.95
Gene length, protein length 594 bp, 198 aa
Immediate neighbours ysnB, rph
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YsnA context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

nucleotide metabolism/ other

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU28360

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: NTP + H2O = NDP + phosphate (according to Swiss-Prot)
  • Protein family: HAM1 NTPase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 2MJP (from Methanococcus jannaschii) PubMed
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Lin, A G McLennan, K Ying, Z Wang, S Gu, H Jin, C Wu, W Liu, Y Yuan, R Tang, Y Xie, Y Mao
Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene.
J Biol Chem: 2001, 276(22);18695-701
[PubMed:11278832] [WorldCat.org] [DOI] (P p)

K Y Hwang, J H Chung, S H Kim, Y S Han, Y Cho
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Nat Struct Biol: 1999, 6(7);691-6
[PubMed:10404228] [WorldCat.org] [DOI] (P p)