Difference between revisions of "YsnA"
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| − | * '''Description:''' | + | * '''Description:''' ITPase<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || ITPase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || purine | + | |style="background:#ABCDEF;" align="center"|'''Function''' || purine metabolism |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]''' | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[nucleotide metabolism/ other]]}} |
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 86: | Line 86: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' http://www.pdb.org/pdb/explore/explore.do?structureId=2MJP 2MJP (from ''Methanococcus jannaschii'') {{PubMed|10404228}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P94558 P94558] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P94558 P94558] | ||
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=References= | =References= | ||
| − | + | <pubmed>10404228 11278832 </pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:59, 1 August 2011
- Description: ITPase
| Gene name | ysnA |
| Synonyms | |
| Essential | no |
| Product | ITPase |
| Function | purine metabolism |
| Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
| MW, pI | 21 kDa, 4.95 |
| Gene length, protein length | 594 bp, 198 aa |
| Immediate neighbours | ysnB, rph |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28360
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NTP + H2O = NDP + phosphate (according to Swiss-Prot)
- Protein family: HAM1 NTPase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: http://www.pdb.org/pdb/explore/explore.do?structureId=2MJP 2MJP (from Methanococcus jannaschii) PubMed
- UniProt: P94558
- KEGG entry: [2]
- E.C. number: 3.6.1.15
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
S Lin, A G McLennan, K Ying, Z Wang, S Gu, H Jin, C Wu, W Liu, Y Yuan, R Tang, Y Xie, Y Mao
Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene.
J Biol Chem: 2001, 276(22);18695-701
[PubMed:11278832]
[WorldCat.org]
[DOI]
(P p)
K Y Hwang, J H Chung, S H Kim, Y S Han, Y Cho
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Nat Struct Biol: 1999, 6(7);691-6
[PubMed:10404228]
[WorldCat.org]
[DOI]
(P p)
