yrrT

yrrT
168

putative AdoMet-dependent methyltransferase

locus
BSU_27280
Molecular weight
24.05 kDa
pI
4.97
Protein length
Gene length
function
methionine salvage
product
putative AdoMet-dependent methyltransferase
essential
no
synonyms
yrrT

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0030 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,787,846  2,788,487
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The protein
Protein family
[wiki|Methyltransferase superfamily] (according to UniProt)
[wiki|Cofactors]
SAM (according to UniProt)
Structure
[PDB|3HNR] (from B. thuringiensis, 55% identity)
[AF|O32029]
Expression and Regulation
Operons
genes
[gene|992A24CF9492965BF0E9EEFBB6F0A06871275068|yrrT]-[gene|5B21D1E73A65B13CE4DDA32ABC71EFA54E8D1D8F|mtnN]-[gene|F195C47849F4F6B4C56E3A386F5D8C84326B01C4|mccA]-[gene|314CB4923D15140E72B0ABAFE3E8BE9CA7310E10|mccB]-[gene|177EFFDCA6E3C3BB840EED13D9F2D71F99B833B6|yrhC]
description
[Pubmed|17056751]
regulation
repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16513748]
regulatory mechanism
[protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]: repression, [Pubmed|16513748], in [regulon|protein:50930C56C27D22715620A350220E3C56ADB41020|cymR regulon]
[protein|2C6386E9A63F410558D168798D077DF91590F454|spx]: activation, [Pubmed|12642660,16885442], in [regulon|protein:2C6386E9A63F410558D168798D077DF91590F454|spx regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|16513748], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|992A24CF9492965BF0E9EEFBB6F0A06871275068|yrrT]→[gene|177EFFDCA6E3C3BB840EED13D9F2D71F99B833B6|yrhC]

2024-03-10 08:58:29

ghost

70

520f018506caa674deba5a8750946c81db19309b

6F8866D3B9D23886BC36B8964568BAC6D245EA17

Biological materials
Mutant
MGNA-A851 (yrrT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/851 NBRP B. subtilis, Japan]
BKE27280 ([gene|992A24CF9492965BF0E9EEFBB6F0A06871275068|yrrT]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTCACACTCCATA,  downstream forward: _UP4_TAAAGTGAAGGGAATGTGAA
BKK27280 ([gene|992A24CF9492965BF0E9EEFBB6F0A06871275068|yrrT]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATTTGTCACACTCCATA,  downstream forward: _UP4_TAAAGTGAAGGGAATGTGAA
References
17056751,16513748,12642660,16885442

992A24CF9492965BF0E9EEFBB6F0A06871275068

Page visits: 4966

Time of last update: 2024-03-28 20:18:52

Author of last update: Jstuelk