YraA

• Description: general stress protein, degradation of damaged thiol-containing proteins
  
  

Gene name	yraA
Synonyms
Essential	no
Product	cysteine proteinase
Function	degradation of damaged thiol-containing proteins
MW, pI	18 kDa, 4.729
Gene length, protein length	507 bp, 169 aa
Immediate neighbours	adhA, sacC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase C56 family (according to Swiss-Prot)

• Paralogous protein(s): YfkM

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: O06006

• KEGG entry: BSU27020

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor: SigB PubMed, SigM PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
2. Jervis et al. 2007. SigM-responsive genes of Bacillus subtilis and their promoters. J. Bacteriol. 189: 4534-4538. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed