Difference between revisions of "YraA"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27020 yraA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27020 yraA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YraA YraA]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 4.729   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 4.729   

Revision as of 11:39, 8 April 2014

  • Description: general stress protein, degradation of damaged thiol-containing proteins, glyoxalase III-like enzyme

Gene name yraA
Synonyms
Essential no
Product glyoxalase III-like enzyme
Function detoxification of methylglyoxal
Gene expression levels in SubtiExpress: yraA
Metabolic function and regulation of this protein in SubtiPathways:
YraA
MW, pI 18 kDa, 4.729
Gene length, protein length 507 bp, 169 aa
Immediate neighbours adhA, sacC
Sequences Protein DNA DNA_with_flanks
Genetic context
YraA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
500px















Categories containing this gene/protein

proteolysis, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

AdhR regulon, SigB regulon, SigM regulon

The gene

Basic information

  • Locus tag: BSU27020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • methylglyoxal --> D-lactate PubMed
  • Protein family: peptidase C56 family (according to Swiss-Prot)
  • Paralogous protein(s): YfkM

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References