YqcF

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  • Description: antitoxin

Gene name yqcF
Synonyms
Essential no
Product antitoxin
Function inhibition of the cytotoxic activity of YqcG
Interactions involving this protein in SubtInteract: YqcF
MW, pI 21 kDa, 4.268
Gene length, protein length 576 bp, 192 aa
Immediate neighbours yqcG, yqxJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqcF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqcF expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU25870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Laura E Holberger, Fernando Garza-Sánchez, James Lamoureux, David A Low, Christopher S Hayes
A novel family of toxin/antitoxin proteins in Bacillus species.
FEBS Lett: 2012, 586(2);132-6
[PubMed:22200572] [WorldCat.org] [DOI] (I p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)