Difference between revisions of "YqaM"

From SubtiWiki
Jump to: navigation, search
Line 24: Line 24:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqzO]]'', ''[[yqaL]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqzO]]'', ''[[yqaL]]''
 
|-
 
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU26260 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU26260 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU26260 Advanced_DNA]
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU26260 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU26260 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU26260 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqaM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqaM_context.gif]]

Revision as of 10:48, 14 May 2013

  • Description: similar to phage-related protein, skin-element

Gene name yqaM
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yqaM
Interactions involving this protein in SubtInteract: YqaM
MW, pI 35 kDa, 5.386
Gene length, protein length 939 bp, 313 aa
Immediate neighbours yqzO, yqaL
Sequences Protein DNA DNA_with_flanks
Genetic context
YqaM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqaM expression.png
























Categories containing this gene/protein

Skin element

This gene is a member of the following regulons

SknR regulon

The gene

Basic information

  • Locus tag: BSU26260

Phenotypes of a mutant

  • overexpression of YqaM causes cell filamentation and abnormal chromosome segregation PubMed
  • overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with DnaC PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): XkdC

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • not expressed during normal growth (SknR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Marie-Françoise Noirot-Gros, Etienne Dervyn, Ling Juan Wu, Peggy Mervelet, Jeffery Errington, S Dusko Ehrlich, Philippe Noirot
An expanded view of bacterial DNA replication.
Proc Natl Acad Sci U S A: 2002, 99(12);8342-7
[PubMed:12060778] [WorldCat.org] [DOI] (P p)