Difference between revisions of "YpqP"

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(Additional information)
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=== Additional information===
 
=== Additional information===
* rearrangement (deletion of the [[SP-beta prophage]] and generation of the ''spsM'' gene) occurs during [[sporulation]] to allow production of spore polysaccharide {{PubMed|25299644}}
+
* rearrangement (deletion of the [[SP-beta prophage]] and generation of the ''spsM'' gene) occurs during [[sporulation]] and in response to DNA damage to allow production of spore polysaccharide {{PubMed|25299644}}
  
 
=The protein=
 
=The protein=

Revision as of 08:28, 10 October 2014

  • Description: C-terminal part of the split gene spsM (together with yodU), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage

Gene name ypqP
Synonyms
Essential no
Product unknown
Function spore envelope polysaccharide biosynthesis
Gene expression levels in SubtiExpress: ypqP
MW, pI - , -
Gene length, protein length 606 bp, SpsM: 341 aa
Immediate neighbours sprA, msrB
Gene sequence (+200bp) Protein sequence
Genetic context
YpqP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YpqP expression.png















Categories containing this gene/protein

membrane proteins, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

  • rearrangement (deletion of the SP-beta prophage and generation of the spsM gene) occurs during sporulation and in response to DNA damage to allow production of spore polysaccharide PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): EpsC (for SpsM)

Extended information on the protein

  • Kinetic information:
  • Domains: SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ypqP (accoriding to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kimihiro Abe, Yuta Kawano, Keito Iwamoto, Kenji Arai, Yuki Maruyama, Patrick Eichenberger, Tsutomu Sato
Developmentally-regulated excision of the SPβ prophage reconstitutes a gene required for spore envelope maturation in Bacillus subtilis.
PLoS Genet: 2014, 10(10);e1004636
[PubMed:25299644] [WorldCat.org] [DOI] (I e)