ptsA

ptsA
168

[category|SW.1.2.2|PTS] EIIA component

locus
BSU_22230
Molecular weight
17.79 kDa
pI
5.29
Protein length
Gene length
function
uptake and phosphorylation of maltose, N-acetylglucosamine, sucrose, and trehalose
product
[category|SW.1.2.2|PTS] EIIA component
essential
no
synonyms
ptsA, ypqE

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2190 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,336,933  2,337,439
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The protein
Protein family
[category|SW.1.2.2|PTS] permease, glucose family [Pubmed|10627040]
[wiki|Domains]
[wiki|PTS EIIA domain] type-1 (aa 36-140) (according to UniProt)
Structure
[PDB|1AX3] (IIA domain of [protein|B5E7EB475434E96786C577AE709A21BD702733D8|ptsG], 46% identity) [pubmed|9593197]
[AF|P50829]
Expression and Regulation
Operons
genes
[gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]
description
[Pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [pubmed|30038046], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]

2024-02-16 04:59:10

Jstuelk

31

48ad7ca7f6eb8fe43bf335611e03b0ef338c4278

A6ACADA40F663DBC47DD06579E142CB31AF113E2

Biological materials
Mutant
MGNA-A477 (ypqE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/477 NBRP B. subtilis, Japan]
QB6099 (aphA3), available in [wiki|Jörg Stülke]'s lab [Pubmed|10627040]
BKE22230 (''ypqE''::''ermC'') (available at the [http://bgsc.org/ BGSC] and in [wiki|Jörg Stülke]'s lab) [pubmed|28189581]
GP1863 (''ypqE''::''ermC'') (available in [wiki|Jörg Stülke]'s lab)
BKE22230 ([gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGTATTTTCTCCCTTCT,  downstream forward: _UP4_TAAGCAGGGCGTATGCCTTG
BKK22230 ([gene|06165870CB68E9C2F1546943CEA668C7790A9647|ptsA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATGTATTTTCTCCCTTCT,  downstream forward: _UP4_TAAGCAGGGCGTATGCCTTG
References
10627040,30038046,9593197

06165870CB68E9C2F1546943CEA668C7790A9647

Page visits: 1854

Time of last update: 2024-03-28 12:09:55

Author of last update: Melvin.boenninger