YplP

• Description: transcriptional activator (for SigL-dependent promoter)
  
  

Gene name	yplP
Synonyms
Essential	no
Product	transcriptional activator (for SigL-dependent promoter)
Function	required for survival at low temperatures
Interactions involving this protein in SubtInteract: YplP
MW, pI	37 kDa, 9.295
Gene length, protein length	993 bp, 331 aa
Immediate neighbours	ilvA, yplQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, cold stress proteins

The gene

Basic information

• Locus tag: BSU21780

Expression

Phenotypes of a mutant

The mutant is cold-sensitive PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YplP-SigL (activation)

• Localization:

Database entries

• Structure:

• UniProt: P54156

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • induced by cold shock (9-fold) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Frank Wiegeshoff, Carsten L Beckering, Michel Debarbouille, Mohamed A Marahiel
Sigma L is important for cold shock adaptation of Bacillus subtilis.
J Bacteriol: 2006, 188(8);3130-3
[PubMed:16585774] [WorldCat.org] [DOI] (P p)

Carsten L Beckering, Leif Steil, Michael H W Weber, Uwe Völker, Mohamed A Marahiel
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis.
J Bacteriol: 2002, 184(22);6395-402
[PubMed:12399512] [WorldCat.org] [DOI] (P p)