Difference between revisions of "YpcP"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 888 bp, 296 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 888 bp, 296 aa  
 
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|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sspL]]'', ''[[ypbS]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sspL]]'', ''[[ypzF]]''
 
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypcP_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypcP_nucleotide.txt    Gene sequence      (+200bp)  ]'''  

Revision as of 12:42, 3 December 2012

  • Description: similar to DNA polymerase I

Gene name ypcP
Synonyms exoA
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ypcP
MW, pI 32 kDa, 5.215
Gene length, protein length 888 bp, 296 aa
Immediate neighbours sspL, ypzF
Gene sequence (+200bp) Protein sequence
Genetic context
YpcP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YpcP expression.png
























Categories containing this gene/protein

DNA replication

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): PolA, one of the two proteins has to be present for viability PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: spore core (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ypcP (according to DBTBS)
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sanae Fukushima, Mitsuhiro Itaya, Hiroaki Kato, Naotake Ogasawara, Hirofumi Yoshikawa
Reassessment of the in vivo functions of DNA polymerase I and RNase H in bacterial cell growth.
J Bacteriol: 2007, 189(23);8575-83
[PubMed:17905985] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)

Stéphane Duigou, S Dusko Ehrlich, Philippe Noirot, Marie-Françoise Noirot-Gros
DNA polymerase I acts in translesion synthesis mediated by the Y-polymerases in Bacillus subtilis.
Mol Microbiol: 2005, 57(3);678-90
[PubMed:16045613] [WorldCat.org] [DOI] (P p)