YorK

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  • Description: single-strand DNA-specific exonuclease

Gene name yorK
Synonyms
Essential no
Product single-strand DNA-specific exonuclease
Function unknown
MW, pI 65 kDa, 6.562
Gene length, protein length 1728 bp, 576 aa
Immediate neighbours yorL, yorJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YorK context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU20350

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

DNA repair/ recombination, SP-beta prophage, phosphoproteins

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RecJ family
  • Paralogous protein(s): YrvE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Tyr-473 PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307] [WorldCat.org] [DOI] (P p)

V A Sutera, E S Han, L A Rajman, S T Lovett
Mutational analysis of the RecJ exonuclease of Escherichia coli: identification of phosphoesterase motifs.
J Bacteriol: 1999, 181(19);6098-102
[PubMed:10498723] [WorldCat.org] [DOI] (P p)