Difference between revisions of "YonT"

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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** the ''[[yonT]]'' mRNA-''[[as-yonT]]'' RNA duplex is degraded by [[RNase III|rnc]] {{PubMed|23300471}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
<pubmed> 20156992 19210617 </pubmed>
+
'''Additional publications:''' {{PubMed|23300471}}
 +
<pubmed> 20156992 19210617</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:29, 10 January 2013

  • Description: toxin

Gene name yonT
Synonyms
Essential no
Product toxin
Function unknown
Gene expression levels in SubtiExpress: yonT
MW, pI 6 kDa, 12.857
Gene length, protein length 174 bp, 58 aa
Immediate neighbours as-yonT, yonS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YonT context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YonT expression.png















Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, SP-beta prophage

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21000

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: panD family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulatory mechanism:
  • Additional information:
    • next to txpA, the yonT mRNA has the strongest Shine-Dalgarno region in B. subtilis PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Elizabeth M Fozo, Kira S Makarova, Svetlana A Shabalina, Natalya Yutin, Eugene V Koonin, Gisela Storz
Abundance of type I toxin-antitoxin systems in bacteria: searches for new candidates and discovery of novel families.
Nucleic Acids Res: 2010, 38(11);3743-59
[PubMed:20156992] [WorldCat.org] [DOI] (I p)

Roula Daou-Chabo, Nathalie Mathy, Lionel Bénard, Ciarán Condon
Ribosomes initiating translation of the hbs mRNA protect it from 5'-to-3' exoribonucleolytic degradation by RNase J1.
Mol Microbiol: 2009, 71(6);1538-50
[PubMed:19210617] [WorldCat.org] [DOI] (I p)