YofA

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  • Description: transcriptional activator of ftsW at the onset of stationary phase

Gene name yofA
Synonyms
Essential no
Product transcriptional activator (LysR family)
Function control of ftsW expression
MW, pI 31 kDa, 6.164
Gene length, protein length 855 bp, 285 aa
Immediate neighbours ggt, yogA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YofA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

The YofA regulon:

The gene

Basic information

  • Locus tag: BSU18420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: yofA (according to DBTBS)
  • Regulation:
    • maximally expressed at the onset of stationary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Zuolei Lu, Michio Takeuchi, Tsutomu Sato
The LysR-type transcriptional regulator YofA controls cell division through the regulation of expression of ftsW in Bacillus subtilis.
J Bacteriol: 2007, 189(15);5642-51
[PubMed:17526699] [WorldCat.org] [DOI] (P p)