Difference between revisions of "YncD"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yncC]]'', ''[[yncE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yncC]]'', ''[[yncE]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17640 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU17640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU17640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU17640 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yncD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yncD_context.gif]]

Revision as of 10:19, 14 May 2013

  • Description: spore coat alanine racemase

Gene name yncD
Synonyms alrB
Essential no
Product spore coat alanine racemase
Function protection of the spore
Gene expression levels in SubtiExpress: yncD
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 43 kDa, 9.593
Gene length, protein length 1182 bp, 394 aa
Immediate neighbours yncC, yncE
Sequences Protein DNA DNA_with_flanks
Genetic context
YncD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YncD expression.png















Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU17640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-alanine = D-alanine (according to Swiss-Prot)
  • Protein family: alanine racemase family (according to Swiss-Prot)
  • Paralogous protein(s): Alr

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon: yncD (according to DBTBS)
  • Regulation:
    • expressed during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814] [WorldCat.org] [DOI] (I p)

Kara J Pierce, Samson P Salifu, Martin Tangney
Gene cloning and characterization of a second alanine racemase from Bacillus subtilis encoded by yncD.
FEMS Microbiol Lett: 2008, 283(1);69-74
[PubMed:18399999] [WorldCat.org] [DOI] (P p)

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Andrea Feucht, Louise Evans, Jeff Errington
Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 10);3023-3034
[PubMed:14523133] [WorldCat.org] [DOI] (P p)