YmcA

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  • Description: antagonist of biofilm repression by SinR, control of the phosphorelay

Gene name ymcA
Synonyms
Essential no
Product antagonist of biofilm repression by SinR
Function control of biofilm formation and the phosphorelay
Gene expression levels in SubtiExpress: ymcA
Interactions involving this protein in SubtInteract: YmcA
MW, pI 16 kDa, 5.086
Gene length, protein length 429 bp, 143 aa
Immediate neighbours ymcB, cotE
Sequences Protein DNA DNA_with_flanks
Genetic context
YmcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YmcA expression.png















Categories containing this gene/protein

transcription factors and their control, phosphorelay, biofilm formation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed during growth and the transition phase, expression is erduced in stationary phase (Spo0A-P) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Valerie J Carabetta, Andrew W Tanner, Todd M Greco, Melissa Defrancesco, Ileana M Cristea, David Dubnau
A complex of YlbF, YmcA and YaaT regulates sporulation, competence and biofilm formation by accelerating the phosphorylation of Spo0A.
Mol Microbiol: 2013, 88(2);283-300
[PubMed:23490197] [WorldCat.org] [DOI] (I p)

Daniel B Kearns, Frances Chu, Steven S Branda, Roberto Kolter, Richard Losick
A master regulator for biofilm formation by Bacillus subtilis.
Mol Microbiol: 2005, 55(3);739-49
[PubMed:15661000] [WorldCat.org] [DOI] (P p)

Steven S Branda, José Eduardo González-Pastor, Etienne Dervyn, S Dusko Ehrlich, Richard Losick, Roberto Kolter
Genes involved in formation of structured multicellular communities by Bacillus subtilis.
J Bacteriol: 2004, 186(12);3970-9
[PubMed:15175311] [WorldCat.org] [DOI] (P p)