Difference between revisions of "YmcA"

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* '''Description:''' antagonist of biofilm repression by [[SinR]] <br/><br/>
+
* '''Description:''' antagonist of biofilm repression by [[SinR]], control of the [[phosphorelay]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || antagonist of biofilm repression by [[SinR]]  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || antagonist of biofilm repression by [[SinR]]  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[biofilm formation]]
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[biofilm formation]] and the [[phosphorelay]]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU17020 ymcA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU17020 ymcA]
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* strongly reduced [[genetic competence]], strongly reduced [[sporulation]] {{PubMed|23490197}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 
** [[YmcA]]-[[YlbF]]-[[YaaT]], this complex stimulates [[Spo0A]] phosphorylation in the [[phosphorelay]] {{PubMed|23490197}}
 
** [[YmcA]]-[[YlbF]]-[[YaaT]], this complex stimulates [[Spo0A]] phosphorylation in the [[phosphorelay]] {{PubMed|23490197}}
 +
** [[YmcA]]-[[Spo0B]] {{PubMed|23490197}}
 +
** [[YmcA]]-[[Spo0F]] {{PubMed|23490197}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** expressed during growth and the transition phase, expression is erduced in stationary phase ([[Spo0A]]-P)  {{PubMed|23490197}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  

Revision as of 13:02, 27 March 2013

  • Description: antagonist of biofilm repression by SinR, control of the phosphorelay

Gene name ymcA
Synonyms
Essential no
Product antagonist of biofilm repression by SinR
Function control of biofilm formation and the phosphorelay
Gene expression levels in SubtiExpress: ymcA
Interactions involving this protein in SubtInteract: YmcA
MW, pI 16 kDa, 5.086
Gene length, protein length 429 bp, 143 aa
Immediate neighbours ymcB, cotE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YmcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YmcA expression.png















Categories containing this gene/protein

transcription factors and their control, biofilm formation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expressed during growth and the transition phase, expression is erduced in stationary phase (Spo0A-P) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References