YlyB

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  • Description: similar to pseudouridylate synthase

Gene name ylyB
Synonyms ylmL
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ylyB
MW, pI 33 kDa, 5.431
Gene length, protein length 909 bp, 303 aa
Immediate neighbours lspA, pyrR
Sequences Protein DNA DNA_with_flanks
Genetic context
YlyB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlyB expression.png















Categories containing this gene/protein

translation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15460

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: RNA uridine = RNA pseudouridine (according to Swiss-Prot)
  • Protein family: S4 RNA-binding domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Charmaine Hoang, Junjun Chen, Caroline A Vizthum, Jason M Kandel, Christopher S Hamilton, Eugene G Mueller, Adrian R Ferré-D'Amaré
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.
Mol Cell: 2006, 24(4);535-45
[PubMed:17188032] [WorldCat.org] [DOI] (P p)