Difference between revisions of "YlxS"

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(Categories containing this gene/protein)
(Extended information on the protein)
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
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* '''[[SubtInteract|Interactions]]:'''
  
* '''Localization:'''
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=== Database entries ===
 
=== Database entries ===

Revision as of 09:44, 2 November 2011

  • Description: similar to 30S ribosomal subunit maturation protein


Gene name ylxS
Synonyms ymxA
Essential no
Product unknown
Function ribosome maturation
MW, pI 17 kDa, 4.482
Gene length, protein length 468 bp, 156 aa
Immediate neighbours polC, nusA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YlxS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU16590

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0090 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Stefan Nord, Göran O Bylund, J Mattias Lövgren, P Mikael Wikström
The RimP protein is important for maturation of the 30S ribosomal subunit.
J Mol Biol: 2009, 386(3);742-53
[PubMed:19150615] [WorldCat.org] [DOI] (I p)

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)

K Shazand, J Tucker, M Grunberg-Manago, J C Rabinowitz, T Leighton
Similar organization of the nusA-infB operon in Bacillus subtilis and Escherichia coli.
J Bacteriol: 1993, 175(10);2880-7
[PubMed:8491709] [WorldCat.org] [DOI] (P p)