yloS

yloS
168

thiamine pyrophosphokinase

locus
BSU_15800
Molecular weight
23.95 kDa
pI
5.22
Protein length
Gene length
function
thiamine salvage
product
thiamine pyrophosphokinase
essential
no
ec
2.7.6.2
synonyms
yloS, thiN

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1564 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,654,730  1,655,374
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The protein
Catalyzed reaction/ biological activity
ATP + thiamine --> AMP + H+ + thiamine diphosphate (according to UniProt)
Protein family
thiamine pyrophosphokinase family (single member, according to UniProt)
Structure
[PDB|3LM8]
[AF|O34664]
Expression and Regulation
Operons
genes
[gene|84447F9A6644EA8A7593BB99B2B69D4377E670E2|prpC]-[gene|23FF4A00C36EC1B7297F51A9EF3579B41F0B7EBA|prkC]-[gene|519D4694B2895EE6F0D38D918F52F27734506848|cpgA]-[gene|8103B8539338B77CF51B16B7FA76783ED2319F13|rpeA]-[gene|0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51|yloS]
description
[Pubmed|22383849]
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[gene|84447F9A6644EA8A7593BB99B2B69D4377E670E2|prpC]→[gene|0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51|yloS]

2024-03-16 08:37:58

Jstuelk

87

f45e3810755c3fba238243b21c1c17e072c8fe47

14D2827FA6BD60210DFADC1BB1FFF0C98DC768FA

Biological materials
Mutant
MGNA-B136 (yloS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1135 NBRP B. subtilis, Japan]
BKE15800 ([gene|0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51|yloS]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15800 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGATTCCTTTCTCT,  downstream forward: _UP4_TAAGCATGTGCTTTCATTCA
BKK15800 ([gene|0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51|yloS]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15800 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGATTCCTTTCTCT,  downstream forward: _UP4_TAAGCATGTGCTTTCATTCA
References
Reviews
19348578,28031352
Original Publications
15150256,16291685

0ACE023DCD6A6BB5A1827D1D997BDFAC3B168C51

Page visits: 1771

Time of last update: 2024-03-28 07:53:41

Author of last update: Melvin.boenninger