Difference between revisions of "YlbQ"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of coenzyme A
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of coenzyme A
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU15110 ylbQ]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15110 ylbQ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.857   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.857   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylbP]]'', ''[[bshC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylbP]]'', ''[[bshC]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13384&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15110 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15110 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15110 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ylbQ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylbQ_context.gif]]

Revision as of 12:45, 13 May 2013

  • Description: 2-dehydropantoate 2-reductase

Gene name ylbQ
Synonyms
Essential no
Product 2-dehydropantoate 2-reductase
Function biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: ylbQ
MW, pI 33 kDa, 5.857
Gene length, protein length 894 bp, 298 aa
Immediate neighbours ylbP, bshC
Sequences Protein DNA Advanced_DNA
Genetic context
YlbQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlbQ expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH (according to Swiss-Prot)
  • Protein family: ketopantoate reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Operon and expression

Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541] [WorldCat.org] [DOI] (I p)