Difference between revisions of "YlbQ"

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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of coenzyme A
 
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of coenzyme A
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU15110 ylbQ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.857   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.857   

Revision as of 09:21, 7 August 2012

  • Description: 2-dehydropantoate 2-reductase

Gene name ylbQ
Synonyms
Essential no
Product 2-dehydropantoate 2-reductase
Function biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: ylbQ
MW, pI 33 kDa, 5.857
Gene length, protein length 894 bp, 298 aa
Immediate neighbours ylbP, bshC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YlbQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlbQ expression.png

























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH (according to Swiss-Prot)
  • Protein family: ketopantoate reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Operon and expression

Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541] [WorldCat.org] [DOI] (I p)