Difference between revisions of "YlbQ"

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* '''Locus tag:''' BSU15110
 
* '''Locus tag:''' BSU15110
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[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ylbQ_1577409_1578305_1 Expression]
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 09:00, 25 January 2012

  • Description: 2-dehydropantoate 2-reductase

Gene name ylbQ
Synonyms
Essential no
Product 2-dehydropantoate 2-reductase
Function biosynthesis of coenzyme A
MW, pI 33 kDa, 5.857
Gene length, protein length 894 bp, 298 aa
Immediate neighbours ylbP, bshC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YlbQ context.gif
This image was kindly provided by SubtiList




Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15110

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (R)-pantoate + NADP+ = 2-dehydropantoate + NADPH (according to Swiss-Prot)
  • Protein family: ketopantoate reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Operon and expression

Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541] [WorldCat.org] [DOI] (I p)