ylaC

168

[wiki|RNA polymerase] ECF-type [wiki|sigma factor] YlaC

locus: BSU_14730

Molecular weight: 20.78 kDa

pI: 9.28

Protein length: 173 aa

Gene length: 522 bp

function: [category|SW.3.2.1|Transcription]

product: [wiki|RNA polymerase] ECF-type [wiki|sigma factor] YlaC

essential: no

synonyms: ylaC

List of homologs in different organisms, belongs to COG1595 (Galperin et al., 2021)

Gene

Coordinates: 1,544,085  1,544,606

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The protein

Protein family

• [wiki|Sigma-70 factor family] (according to UniProt)
• [wiki|ECF subfamily] (according to UniProt)

Structure

• [PDB|5WUQ] ([protein|search|SigW ]in complex with the cytoplasmic domain of [protein|4E720917045032E8B45CB8AF6E5C13AE0E48EE33|rsiW], 33% identity) [pubmed|28319136]
• [AF|O07627]

Effectors of protein activity

• [protein|B454D14B33E2C11F0BB0A1D1BB743FA64981A966|ylaD] acts as anti-sigma [Pubmed|16728958]

Biological materials

Mutant

• MGNA-B356 (ylaC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1355 NBRP B. subtilis, Japan]
• 1A908 ( ''ylaC''::''kan''), [Pubmed|15838020], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A908&Search=1A908 BGSC]
• BKE14730 ([gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CTCAATGGAATCCCTATGCT,  downstream forward: _UP4_AAAAGTAGAGAGGAGGAGCG
• BKK14730 ([gene|544344B61A804F367BB726976E0C87B61998490A|ylaC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14730 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CTCAATGGAATCCCTATGCT,  downstream forward: _UP4_AAAAGTAGAGAGGAGGAGCG

References

Reviews

• 24921931

Original Publications

• 16501307,16728958,17675383,20817771,28319136,29760236