Difference between revisions of "YkuV"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
 
=The protein=
 
=The protein=
  

Revision as of 22:14, 30 November 2010

  • Description: thiol disulfide oxidoreductase

Gene name ykuV
Synonyms
Essential no
Product thiol disulfide oxidoreductase
Function protection of proteins against oxidative damage
MW, pI 17 kDa, 6.333
Gene length, protein length 459 bp, 153 aa
Immediate neighbours ykuU, rok
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YkuV context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU14230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 2B5X (reduced form), 2B5Y (oxidized form)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

Xinxin Zhang, Yunfei Hu, Xianrong Guo, Ewen Lescop, You Li, Bin Xia, Changwen Jin
The Bacillus subtilis YkuV is a thiol:disulfide oxidoreductase revealed by its redox structures and activity.
J Biol Chem: 2006, 281(12);8296-304
[PubMed:16418167] [WorldCat.org] [DOI] (P p)