Difference between revisions of "YkuQ"

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* '''Additional information:'''
 
* '''Additional information:'''
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** number of protein molecules per cell (minimal medium with glucose and ammonium): 3224 {{PubMed|24696501}}
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** number of protein molecules per cell (complex medium with amino acids, without glucose): 9397 {{PubMed|24696501}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 09:42, 17 April 2014

  • Description: similar to tetrahydrodipicolinate succinylase

Gene name ykuQ
Synonyms
Essential yes PubMed
Product similar to tetrahydrodipicolinate succinylase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuQ
Metabolic function and regulation of this protein in SubtiPathways:
ykuQ
MW, pI 24 kDa, 4.678
Gene length, protein length 708 bp, 236 aa
Immediate neighbours ykuP, dapI
Sequences Protein DNA DNA_with_flanks
Genetic context
YkuQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkuQ expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14180

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + L-2-acetamido-6-oxoheptanedioate (according to Swiss-Prot)
  • Protein family: transferase hexapeptide repeat family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 3R8Y (from Bacillus anthracis, 80% identity, 96% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 3224 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 9397 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References