Difference between revisions of "YkuQ"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14180 ykuQ]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU14180 ykuQ]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/lys_threo.html Lys, Thr]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ykuQ ykuQ]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 4.678   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 4.678   

Revision as of 10:39, 7 January 2014

  • Description: similar to tetrahydrodipicolinate succinylase

Gene name ykuQ
Synonyms
Essential yes PubMed
Product similar to tetrahydrodipicolinate succinylase
Function biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuQ
Metabolic function and regulation of this protein in SubtiPathways:
ykuQ
MW, pI 24 kDa, 4.678
Gene length, protein length 708 bp, 236 aa
Immediate neighbours ykuP, dapI
Sequences Protein DNA DNA_with_flanks
Genetic context
YkuQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkuQ expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14180

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + L-2-acetamido-6-oxoheptanedioate (according to Swiss-Prot)
  • Protein family: transferase hexapeptide repeat family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 3R8Y (from Bacillus anthracis, 80% identity, 96% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References