Difference between revisions of "YkoY"
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| − | * '''Description:''' | + | * '''Description:''' membrane protein, may be involved in manganese detoxification<br/><br/> |
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[sporulation proteins]]}} | + | {{SubtiWiki category|[[sporulation proteins]]}}, |
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
Revision as of 17:45, 26 March 2015
- Description: membrane protein, may be involved in manganese detoxification
| Gene name | ykoY |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | unknown |
| Gene expression levels in SubtiExpress: ykoY | |
| MW, pI | 35 kDa, 9.731 |
| Gene length, protein length | 972 bp, 324 aa |
| Immediate neighbours | ykoX, sigI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
sporulation proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13440
Phenotypes of a mutant
Database entries
- BsubCyc: BSU13440
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU13440
- Structure:
- UniProt: O34997
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon: ykoY PubMed
- Regulation:
- induced in the presence of Mn2+ (yybP-ykoY motif) PubMed
- Regulatory mechanism:
- yybP-ykoY motif, riboswitch, antitermination in the presence of the ligand Mn2+ PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ian R Price, Ahmed Gaballa, Fang Ding, John D Helmann, Ailong Ke
Mn(2+)-sensing mechanisms of yybP-ykoY orphan riboswitches.
Mol Cell: 2015, 57(6);1110-1123
[PubMed:25794619]
[WorldCat.org]
[DOI]
(I p)
Michael Dambach, Melissa Sandoval, Taylor B Updegrove, Vivek Anantharaman, L Aravind, Lauren S Waters, Gisela Storz
The ubiquitous yybP-ykoY riboswitch is a manganese-responsive regulatory element.
Mol Cell: 2015, 57(6);1099-1109
[PubMed:25794618]
[WorldCat.org]
[DOI]
(I p)
Jeffrey E Barrick, Keith A Corbino, Wade C Winkler, Ali Nahvi, Maumita Mandal, Jennifer Collins, Mark Lee, Adam Roth, Narasimhan Sudarsan, Inbal Jona, J Kenneth Wickiser, Ronald R Breaker
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.
Proc Natl Acad Sci U S A: 2004, 101(17);6421-6
[PubMed:15096624]
[WorldCat.org]
[DOI]
(P p)
