YkkE

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  • Description: formyltetrahydrofolate deformylase

Gene name ykkE
Synonyms purU
Essential no
Product formyltetrahydrofolate deformylase
Function purine nucleotide synthesis
Gene expression levels in SubtiExpress: ykkE
MW, pI 34 kDa, 5.949
Gene length, protein length 900 bp, 300 aa
Immediate neighbours ykkD, proB
Sequences Protein DNA DNA_with_flanks
Genetic context
YkkE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkkE expression.png



















Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU13110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + H2O = formate + tetrahydrofolate (according to Swiss-Prot)
  • Protein family: ACT domain (according to Swiss-Prot)
  • Paralogous protein(s): PurN

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References