YkkE

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  • Description: formyltetrahydrofolate deformylase

Gene name ykkE
Synonyms purU
Essential no
Product formyltetrahydrofolate deformylase
Function purine nucleotide synthesis
MW, pI 34 kDa, 5.949
Gene length, protein length 900 bp, 300 aa
Immediate neighbours ykkD, proB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YkkE context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU13110

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + H2O = formate + tetrahydrofolate (according to Swiss-Prot)
  • Protein family: ACT domain (according to Swiss-Prot)
  • Paralogous protein(s): PurN

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References