ykkD

168

putative guanidine exporter

locus: BSU_13100

Molecular weight: 11.19 kDa

pI: 8.62

Protein length: 105 aa

Gene length: 318 bp

function: export/ detoxification of guanidine

product: subunit of guanidine exporter

essential: no

synonyms: ykkD

List of homologs in different organisms, belongs to COG2076 (Galperin et al., 2021)

Gene

Coordinates: 1,376,855  1,377,172

Advertisement

The protein

Protein family

• paired small multidrug resistance  protein family ([wiki|PSMR family]) [Pubmed|17942072]
• [wiki|drug/metabolite transporter (DMT) superfamily] (according to UniProt)
• [wiki|Small multidrug resistance (SMR) (TC 2.A.7.1) family] (according to UniProt)

Structure

• [PDB|3B5D] (from E. coli, 29% identity) [pubmed|18024586]
• [AF|P49857]

[wiki|Localization]

• cell membrane (according to UniProt)

Biological materials

Mutant

• MGNA-A748 (ykkD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/748 NBRP B. subtilis, Japan]
• BKE13100 ([gene|5001019AD87FEF7D7A920D570C1053D476F7F20C|ykkD]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13100 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATAAACTGATCCAGTGCA,  downstream forward: _UP4_TAAATTGATTTTTATCAAAT
• BKK13100 ([gene|5001019AD87FEF7D7A920D570C1053D476F7F20C|ykkD]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13100 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAATAAACTGATCCAGTGCA,  downstream forward: _UP4_TAAATTGATTTTTATCAAAT

References

Reviews

• 17942072

Original Publications

• 10735877,21317561,27989440,27120414,18024586