Difference between revisions of "YkfC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall metabolism
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall metabolism
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU12990 ykfC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU12990 ykfC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 6.346   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 6.346   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykfB]]'', ''[[ykfD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykfB]]'', ''[[ykfD]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13156&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12990 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12990 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12990 Advanced_DNA]
 
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Revision as of 12:37, 13 May 2013

  • Description: D-glutamyl-L-amino acid peptidase

Gene name ykfC
Synonyms
Essential no
Product D-glutamyl-L-amino acid peptidase
Function cell wall metabolism
Gene expression levels in SubtiExpress: ykfC
MW, pI 32 kDa, 6.346
Gene length, protein length 888 bp, 296 aa
Immediate neighbours ykfB, ykfD
Sequences Protein DNA Advanced_DNA
Genetic context
YkfC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YkfC expression.png


























Categories containing this gene/protein

cell wall/ other

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12990

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cleaves L-Ala-γ-D-Glu dipeptides from cell wall peptides PubMed
  • Protein family: nlpC/p60 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulatory mechanism: CodY: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)

All publications: PubMed