Difference between revisions of "YisP"

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* '''Description:''' unknown <br/><br/>
+
* '''Description:''' production of squalene-derived polyisoprenoids <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || squalene synthase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[KinC]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258   
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
+
* complete loss of pellicle-forming ability {{PubMed|20713508}}
 
=== Database entries ===
 
=== Database entries ===
  
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* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''Cofactor(s):''' NADH  {{PubMed|20713508}}
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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=References=
 
=References=
 
+
<pubmed> 20713508 19935659</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:01, 14 October 2010

  • Description: production of squalene-derived polyisoprenoids

Gene name yisP
Synonyms yucD
Essential no
Product squalene synthase
Function control of KinC activity
MW, pI 31 kDa, 7.258
Gene length, protein length 822 bp, 274 aa
Immediate neighbours yizA, yisQ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YisP context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU10810

Phenotypes of a mutant

  • complete loss of pellicle-forming ability PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

The gene is annotated in KEGG as an ortholog of phytoene synthase EC 2.5.1.32. No EC annotation is available in Swiss-Prot/MetaCSwiss-Prot/MetaCyc.literature/experimental evidence supporting the annotation is available. PubMed

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Daniel López, Roberto Kolter
Functional microdomains in bacterial membranes.
Genes Dev: 2010, 24(17);1893-902
[PubMed:20713508] [WorldCat.org] [DOI] (I p)

Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659] [WorldCat.org] [DOI] (I p)