YhfU

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  • Description: high capacity biotin transporter

Gene name yhfU
Synonyms bioY
Essential no
Product high capacity biotin transporter
Function uptake of biotin
MW, pI 19 kDa, 10.681
Gene length, protein length 558 bp, 186 aa
Immediate neighbours yhfT, hemAT
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhfU context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transporters/ other, biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10370

Expression

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: uptake of biotin PubMed
  • Protein family: bioY family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews: PubMed

Original publications

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Peter Hebbeln, Dmitry A Rodionov, Anja Alfandega, Thomas Eitinger
Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module.
Proc Natl Acad Sci U S A: 2007, 104(8);2909-14
[PubMed:17301237] [WorldCat.org] [DOI] (P p)