YhcF

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  • Description: similar to transcriptional regulator (GntR family)

Gene name yhcF
Synonyms
Essential no
Product transcriptional regulator (GntR family)
Function unknown
Gene expression levels in SubtiExpress: yhcF
MW, pI 13 kDa, 5.457
Gene length, protein length 363 bp, 121 aa
Immediate neighbours yhcE, yhcG
Sequences Protein DNA DNA_with_flanks
Genetic context
YhcF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhcF expression.png
























Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU09060

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GntR family of transcription regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3NEU (similar protein from Listeria innocua, 38% identity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Martin Lehnik-Habrink, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, Christina Herzberg, Jörg Stülke
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Mol Microbiol: 2011, 81(6);1459-73
[PubMed:21815947] [WorldCat.org] [DOI] (I p)