YhcF

From SubtiWiki
Revision as of 13:09, 10 August 2012 by Raphael2215 (talk | contribs)
Jump to: navigation, search
  • Description: similar to transcriptional regulator (GntR family)

Gene name yhcF
Synonyms
Essential no
Product transcriptional regulator (GntR family)
Function unknown
Gene expression levels in SubtiExpress: yhcF
MW, pI 13 kDa, 5.457
Gene length, protein length 363 bp, 121 aa
Immediate neighbours yhcE, yhcG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhcF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhcF expression.png
























Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU09060

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GntR family of transcription regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3NEU (similar protein from Listeria innocua, 38% identity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947