YhcF

• Description: similar to transcriptional regulator (GntR family)
  
  

Gene name	yhcF
Synonyms
Essential	no
Product	transcriptional regulator (GntR family)
Function	unknown
Gene expression levels in SubtiExpress: yhcF
MW, pI	13 kDa, 5.457
Gene length, protein length	363 bp, 121 aa
Immediate neighbours	yhcE, yhcG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control

The gene

Basic information

• Locus tag: BSU09060

Database entries

• BsubCyc: BSU09060

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GntR family of transcription regulators

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU09060

• Structure: 3NEU (similar protein from Listeria innocua, 38% identity)

• UniProt: P54590

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yhbI-yhbJ-yhcA-yhcB-yhcC-yhcD-yhcE-yhcF-yhcG-yhcH-yhcI PubMed

• Expression browser: yhcF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Martin Lehnik-Habrink, Marc Schaffer, Ulrike Mäder, Christine Diethmaier, Christina Herzberg, Jörg Stülke
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y.
Mol Microbiol: 2011, 81(6);1459-73
[PubMed:21815947] [WorldCat.org] [DOI] (I p)