Difference between revisions of "YhcA"

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* '''Description:''' similar to multidrug resistance protein <br/><br/>
 
 
 
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Revision as of 13:13, 10 August 2012

  • Description: similar to multidrug resistance protein

Gene name yhcA
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yhcA
MW, pI 58 kDa, 9.49
Gene length, protein length 1596 bp, 532 aa
Immediate neighbours yhbJ, yhcB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YhcA expression.png
























Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU09010

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: EmrB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947