YgaF

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  • Description: similar to thioredoxin-dependent hydroperoxide peroxidase

Gene name ygaF
Synonyms
Essential no
Product unknown
Function resistance against oxidative stress
Gene expression levels in SubtiExpress: ygaF
MW, pI 17 kDa, 5.857
Gene length, protein length 471 bp, 157 aa
Immediate neighbours gsaB, perR
Sequences Protein DNA Advanced_DNA
Genetic context
YgaF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YgaF expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU08720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • The E. coli homolog: bcp

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH (according to Swiss-Prot)
  • Protein family: thioredoxin domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

W Jeong, M K Cha, I H Kim
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) family.
J Biol Chem: 2000, 275(4);2924-30
[PubMed:10644761] [WorldCat.org] [DOI] (P p)