YgaF

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  • Description: similar to thioredoxin-dependent hydroperoxide peroxidase

Gene name ygaF
Synonyms
Essential no
Product unknown
Function resistance against oxidative stress
MW, pI 17 kDa, 5.857
Gene length, protein length 471 bp, 157 aa
Immediate neighbours gsaB, perR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YgaF context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU08720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • The E. coli homolog: bcp

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH (according to Swiss-Prot)
  • Protein family: thioredoxin domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

W Jeong, M K Cha, I H Kim
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) family.
J Biol Chem: 2000, 275(4);2924-30
[PubMed:10644761] [WorldCat.org] [DOI] (P p)