Difference between revisions of "YgaF"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resistance against oxidative stress
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistance against oxidative stress
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU08720 ygaF]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU08720 ygaF]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 5.857   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 5.857   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gsaB]]'', ''[[perR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gsaB]]'', ''[[perR]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12700&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU08720 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU08720 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU08720 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ygaF_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ygaF_context.gif]]

Revision as of 12:24, 13 May 2013

  • Description: similar to thioredoxin-dependent hydroperoxide peroxidase

Gene name ygaF
Synonyms
Essential no
Product unknown
Function resistance against oxidative stress
Gene expression levels in SubtiExpress: ygaF
MW, pI 17 kDa, 5.857
Gene length, protein length 471 bp, 157 aa
Immediate neighbours gsaB, perR
Sequences Protein DNA Advanced_DNA
Genetic context
YgaF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YgaF expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU08720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

  • The E. coli homolog: bcp

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH (according to Swiss-Prot)
  • Protein family: thioredoxin domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

W Jeong, M K Cha, I H Kim
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/Alkyl hydroperoxide peroxidase C (AhpC) family.
J Biol Chem: 2000, 275(4);2924-30
[PubMed:10644761] [WorldCat.org] [DOI] (P p)