Difference between revisions of "YfnI"

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(Extended information on the protein)
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* induction of [[SigM]] and [[SigX]] activities {{PubMed|23103977}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ltaSA_796314_798233_1 yfnI] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ltaSA_796314_798233_1 yfnI] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17434969 PubMed]
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* '''[[Sigma factor]]:''' [[SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17434969 PubMed]
  
 
* '''Regulation:'''
 
* '''Regulation:'''
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<pubmed> 21388439 </pubmed>
 
<pubmed> 21388439 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>17434969,,18957862 17218307 19229300 21255105, </pubmed>
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<pubmed>17434969,23103977,18957862 17218307 19229300 21255105, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 17:27, 1 November 2012

  • Description: polyglycerolphosphate lipoteichoic acid synthase, general stress protein, major secreted protein, required for survival at low temperature (4°C)

Gene name yfnI
Synonyms yetP, ltaSA
Essential no
Product minor lipoteichoic acid synthetase
Function biosynthesis of lipoteichoic acid
Gene expression levels in SubtiExpress: yfnI
MW, pI 73 kDa, 5.951
Gene length, protein length 1917 bp, 639 aa
Immediate neighbours yetO, yfnH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YfnI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfnI expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, cell envelope stress proteins (controlled by SigM, V, W, X, Y), phosphoproteins

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU07260

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: LTA synthase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on (Thr-311 OR Ser-312) PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: yfnI (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Additional reviews: PubMed

Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439] [WorldCat.org] [DOI] (I p)

Original publications

Michihiro Hashimoto, Takahiro Seki, Satoshi Matsuoka, Hiroshi Hara, Kei Asai, Yoshito Sadaie, Kouji Matsumoto
Induction of extracytoplasmic function sigma factors in Bacillus subtilis cells with defects in lipoteichoic acid synthesis.
Microbiology (Reading): 2013, 159(Pt 1);23-35
[PubMed:23103977] [WorldCat.org] [DOI] (I p)

Mirka E Wörmann, Rebecca M Corrigan, Peter J Simpson, Steve J Matthews, Angelika Gründling
Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes.
Mol Microbiol: 2011, 79(3);566-83
[PubMed:21255105] [WorldCat.org] [DOI] (I p)

Kathrin Schirner, Jon Marles-Wright, Richard J Lewis, Jeff Errington
Distinct and essential morphogenic functions for wall- and lipo-teichoic acids in Bacillus subtilis.
EMBO J: 2009, 28(7);830-42
[PubMed:19229300] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Adrian J Jervis, Penny D Thackray, Chris W Houston, Malcolm J Horsburgh, Anne Moir
SigM-responsive genes of Bacillus subtilis and their promoters.
J Bacteriol: 2007, 189(12);4534-8
[PubMed:17434969] [WorldCat.org] [DOI] (P p)

Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307] [WorldCat.org] [DOI] (P p)