yfkJ
168
general stress protein, protein tyrosine phosphatase, required for protection against paraquat stress
locus
BSU_07880
Molecular weight
17.13 kDa
pI
4.56
function
survival of stress conditions
product
protein tyrosine phosphatase
essential
no
ec
3.1.3.48
synonyms
yfkJ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0394 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
862,004 862,474
The protein
Catalyzed reaction/ biological activity
H2O + O-phospho-L-tyrosyl-[protein] --> L-tyrosyl-[protein] + phosphate (according to UniProt)
Protein family
low molecular weight phosphotyrosine protein phosphatase family (with [protein|DB3527FB78D0B7C144D1699D665788184F19AFE0|arsC] and [protein|1BAD28287257F82F907706AFD2E8FF5F3BD1B57B|ywlE], according to UniProt)
Structure
[PDB|4ETM]
[AF|O35016]
Paralogous protein(s)
[protein|1BAD28287257F82F907706AFD2E8FF5F3BD1B57B|ywlE]
Biological materials
Mutant
MGNA-C266 (yfkJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2264 NBRP B. subtilis, Japan]
BKE07880 ([gene|2CEFD8D9692D062CC09E3DEDA1A4015C76BC4167|yfkJ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGTGCAACCTCCCTA, downstream forward: _UP4_TTGTGAGTGAAAGGAGAATT
BKK07880 ([gene|2CEFD8D9692D062CC09E3DEDA1A4015C76BC4167|yfkJ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07880 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATGTGCAACCTCCCTA, downstream forward: _UP4_TTGTGAGTGAAAGGAGAATT
References
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Time of last update: 2024-04-24 00:59:30
Author of last update: Melvin.boenninger